Review · Sleep and energy

Yu Sleep review: what we could check, and what the label leaves out

Yu Sleep is a dropper formula sold for deeper sleep and fewer 3 a.m. wake-ups. It names ten ingredients and publishes the amount of one. We looked at the research behind each, and at the terms behind the money-back promise.

By Grant Whitaker, Editor · Updated October 23, 2026 · 20 studies checked on PubMed

What Yu Sleep is

Yu Sleep is a liquid supplement in a dropper bottle. The directions are two droppers under the tongue, held for about thirty seconds, roughly 30 minutes before bed. It is sold online through BuyGoods, a third-party retailer, and the refund page gives a return address in Aurora, Colorado, under the Yu Sleep name. We found no other company name on the sales or policy pages.

The sales video and pages credit the formula to a "Dr. Andrew Collins" and a sleep research team. No institution, publication or license is given, so we could not check those credentials. Most of the customer stories on the page come from women in midlife; nothing in the formula is specific to either sex, and the product suits men over 50 as much as anyone.

The central pitch is that Yu Sleep "restores your brain's natural sleep pressure system" built on adenosine, rather than forcing sleep with a large melatonin dose. The page also says the drops are "nano-emulsified" for "99% absorption" compared with 22% for capsules, cites a study of 3,400 participants, and says 67% of customers report weight loss linked to GLP-1. We come back to each of these below.

The formula next to the research

There is no Supplement Facts panel on any Yu Sleep page we could reach: not on the video page, not on the product page and not in the policy pages. The bottles appear only in customer photos, where the label text cannot be read. The sales page lists the ingredients and gives one dose, 0.9 mg of melatonin. That limits what this table can say.

Melatonin: the one dose we can check, and a sensible one

Melatonin is the best-supported ingredient here, and the dose choice deserves credit. In an MIT trial, adults over 50 with low sleep efficiency took 0.1, 0.3 or 3 mg 30 minutes before bed for a week each, with sleep measured in the lab. The 0.3 mg dose restored sleep efficiency and brought blood melatonin back to a normal night-time level. The 3 mg dose also improved sleep but left melatonin elevated into the daytime and lowered body temperature. People who already slept normally saw no change at any dose ^[1]. Yu Sleep's 0.9 mg falls between the two effective doses.

Keep the size of the effect in mind. A meta-analysis of 19 trials with 1,683 people found melatonin shortened the time to fall asleep by about 7 minutes and added about 8 minutes of sleep on average compared with placebo ^[2]. A later review of 23 trials found a modest improvement in sleep quality scores, with wide differences between studies ^[3]. Useful for some people, but small.

Tart cherry: small trials, using juice

In a crossover trial of 20 healthy adults, a tart cherry juice concentrate taken for 7 days raised urinary melatonin and increased total sleep time and sleep efficiency measured by a wrist monitor ^[4]. In a pilot study of adults over 50 with insomnia, 240 mL of juice twice a day for two weeks added 84 minutes of sleep on lab testing; only 8 people completed it, and 3 others were excluded and referred after sleep apnea was found ^[5]. A 2025 systematic review of seven studies called the evidence promising but limited and inconsistent in dose ^[6]. Yu Sleep uses an extract in an undisclosed amount, which is not what these trials gave.

5-HTP: one small trial in older adults

5-HTP is the building block the body uses to make serotonin. In a 12-week trial in Singapore, 30 adults around 66 years old took 100 mg a day or nothing. Poor sleepers in the 5-HTP group improved on some sleep quality measures, and the trial was single-blinded, without a placebo pill ^[7]. That is a thin base, and 5-HTP carries the interaction concern covered in the safety section.

Magnesium, L-theanine and lemon balm: modest, mostly self-reported

A 2025 trial gave 155 adults reporting poor sleep 250 mg of elemental magnesium as bisglycinate. Insomnia scores improved more than with placebo at four weeks, but the effect was small ^[8]. A 2026 systematic review of twelve trials rated the overall certainty of magnesium for sleep as low to very low ^[9]. A dose like 250 mg of elemental magnesium is also hard to fit in two droppers of liquid, which is one more reason the missing label matters.

L-theanine, an amino acid from tea, was given at 200 mg a day for four weeks to 30 healthy adults in a crossover trial; sleep questionnaire scores improved, with tablets supplied by an L-theanine maker ^[10]. A crossover trial of a standardized lemon balm extract in phytosome form reported lower insomnia scores than placebo; several authors were consultants for the company behind the extract ^[14].

Apigenin, GABA and the B vitamins: the weakest links

We found no human sleep trial of apigenin on its own. The closest evidence is chamomile, which contains it: 60 adults aged 60 or older in a nursing home who took 200 mg of chamomile extract twice a day for 28 days reported better sleep quality than a control group ^[13]. For GABA taken by mouth, a systematic review of 14 placebo-controlled trials on stress and sleep found "very limited evidence" of sleep benefits ^[11]. The GABA plus L-theanine study on the seller's reference list was done in mice and rats ^[12].

For vitamin B6, the reference the seller cites gave 240 mg before bed for five nights. It increased how much people remembered of their dreams but did not significantly change other sleep measures, and the B complex group reported worse sleep quality ^[15]. Another B6 reference on the list is a mouse and cell study ^[16]. For vitamin B2, the seller links a blog post and a conference abstract rather than a trial, and our PubMed search found no human B2 sleep trial to set against it.

What the marketing claims, and what we could verify

• "3,400 participants, six months," with 89% improving in days and sleep scores rising from 43 to 81. No authors, journal or registry number are given. We found nothing matching it on PubMed. We cannot verify it and do not rely on it.
• "99% absorption" from nano-emulsified drops versus "22%" for capsules. No source is given for either number. We found no published study of this product's absorption.
• "Restores the sleep pressure system." Adenosine does build up during waking hours, but none of the trials above measured adenosine, and we found no study showing this formula changes it.
• Weight loss through GLP-1, and results that last after you stop. These come from customer surveys the seller describes but does not publish. We found no trial of Yu Sleep on weight, and none of the ingredient trials above tested lasting effects after stopping.
• The seller's 20 references. We opened the PubMed ones. Several are genuine human trials or reviews (melatonin, tart cherry, 5-HTP, GABA), which we cite above. Others are animal or cell studies, a children's study of night terrors, a Parkinson's disease study, a blog post and a conference abstract. None tested Yu Sleep.

Price, packages and refund policy

The sales page sells Yu Sleep by the month, one bottle per month, with no single-bottle option. The page says this is deliberate, to make sure buyers stay on it long enough. Prices when we checked:

• 6-month supply: $49 a month ($294 total), free US shipping, three digital bonuses. About $1.63 a night.
• 3-month supply: $59 a month ($177 total), with digital bonuses. Shipping is shown at checkout.
• 2-month supply: $69 a month ($138 total), plus shipping.

The checkout is a one-time payment, with an optional "Subscribe and Save" discount you would have to choose. The shipping policy page lists $14.95 for US delivery in one place and $9.95 for one unit in another.

The refund terms are where we would slow down. The sales page promises a 60-day "100% money-back" guarantee with "no questions asked." The separate refund policy page says refunds are issued at "around 85%" of the purchase price because shipping and handling are kept, return postage is paid by you, you must mail the product back with your order number, and a second purchase after a refund is not eligible at all. It also asks for 21 nights in a row before deciding. Read that page before you buy.

Safety

Two of the ingredients act on brain chemistry in ways that matter if you take medication.

• Sedatives and sleep medications. In adults 55 and older, melatonin taken with zolpidem (a prescription sleep drug) made the drug's impairment of driving, coordination and memory worse in the hours after the dose ^[17]. If you use any prescription sleep aid, benzodiazepine, opioid or alcohol at night, ask your doctor before adding Yu Sleep.
• Antidepressants. 5-HTP raises serotonin, and serotonin syndrome is one of the safety issues reviewed for it ^[19]. The antidepressant fluvoxamine raised peak blood melatonin about 17-fold in a small study of healthy men ^[18]. Do not combine Yu Sleep with an SSRI, SNRI, MAO inhibitor, triptan or similar drug without your doctor's approval.
• Label accuracy. When 31 melatonin supplements were tested, most did not contain their labeled amount within 10%, and some also contained serotonin ^[20]. We have no independent test of Yu Sleep, and without a published label there is less to check it against.

Loud snoring, pauses in breathing, waking up gasping, or heavy daytime sleepiness are reasons to see a doctor about sleep apnea; a supplement can hide the tiredness without addressing the cause. Talk to your doctor before starting Yu Sleep, especially if you take any prescription medication, and get medical care for sleep problems that are new or getting worse. Results vary from person to person.

What we liked and what gave us pause

Frequently asked questions

Where can I buy Yu Sleep?

Through the seller's website, which sends orders to the BuyGoods checkout. We did not find it in stores, and listings elsewhere may not be covered by the seller's refund policy.

How much melatonin is in Yu Sleep?

The sales page says 0.9 mg per serving of two droppers. It is the only dose the seller publishes.

How long before I notice anything?

Results vary. The melatonin trials ran from one week to several months, and the seller's own refund page asks for 21 nights in a row before judging it. If nothing has changed after a few weeks, that is worth discussing with your doctor.

Can I take it with my prescription sleep aid or antidepressant?

Not without asking your doctor first. Melatonin can add to the effects of sedating drugs, and 5-HTP adds to serotonin.

How we reviewed Yu Sleep

We read the Yu Sleep video page, product page, refund policy, shipping policy and terms, and looked for a Supplement Facts label (none was published). We searched PubMed for human trials of each listed ingredient on sleep, opened the PubMed references the seller cites, and compared trial doses with the one dose the seller discloses. We did not test the product on people, and nobody at Stark Verve is a medical professional. Read our editorial policy to learn how we choose and update reviews. Stark Verve earns a commission if you buy through our links; that never changes what we write about the evidence.